This is a long-term autoimmune disease that involves abnormal skin patches that are reddish, itchy as well as scaly. Skin injury may cause psoriatic skin changes on such a spot. Psoriasis differs when it comes to severity and can be small, localized, or even entire body coverage. The disease is of five different types including inverse, pustular, erythrodermic, plague, inverse and guttate, with plaque psoriasis being the most common. The diseases mostly affect the scalp, along the belly bottom, shins, and the back of the arms. It is a disease believed to be a generic one in general and it is triggered by the environment.
Psoriasis has no cure. But certain treatments have been available to assist with the symptoms. These include steroid creams, ultraviolet light, vitamin D3 cream, as well as immune system-suppressing drugs like methotrexate.
The lack of significant improvement for most people with psoriasis skin plaques after topical treatment with creams and ointments is evident. For people with a complete body infection, topical treatment becomes impractical. Modern treatments for psoriasis are “systematic,” meaning that the affect the entire body. Such treatments are more convenient as well as efficient compared to topical therapies. On the other hand, the systematic treatment drugs have certain side effects.
A Comparison Between Systematic and Topical Psoriasis Treatments
Topical treatments involve anything applied on the infected skin. They have little or no side effects at all and no absorption into a person’s bloodstream. The common ones include Ultraviolet light or phototherapy, which is focused on skin areas that are affected only and Corticoids, for instance, fluocinonide or hydrocortisone, anthralin, tazarotene, moisturizers, coal tar, tacrolimus, calcitriol, and calcipotriene.
Systematic treatments frequently act on a person’s immune system to mitigate the activity of psoriasis over huge areas of the body. They are commonly utilized in treating moderate to serious psoriasis. Modern systematic treatments available include ultraviolet light or phototherapy treatment to the whole body, oral drugs like methotrexate, acitretin, cyclosporine, and apremilast. Other treatments include biological therapies, which include etanercept (Enbrel), adalimumab (Humira), secukinumab (Cosentyx) ustekinumab (Stelara) and infliximab (Remicade). All these happen to be injectable drugs. One thing to note is that despite systematic treatments being effective than tropical ones by far, they are more expensive and have possible side effects.
Choosing Modern Psoriasis Treatment
According to research, most individuals with limited psoriasis fail to apply topical therapies with consistency. It is not that such treatments are not effective, but most people fail to give them the opportunity to work mainly because they are inconvenient and messy. If directed by a physician to use the, it is better to apply the treatment as directed. It is not wrong to switch to a systematic treatment for the purpose of convenience; however, seeking knowledge on their benefits as well as risks involved is important.
The severity of the disease is the most important factor to put in mind when considering the systematic paralysis treatment. Doctors use the following criteria to categorize severity of infection:
1. Limited or mild to moderate psoriasis- infection below 3% of entire body surface
2. Moderate psoriasis- infection between 3% and 10% of the entire body surface
3. Severe Psoriasis- more than 10% of the body surface is affected.
Topical treatments should be utilized to manage limited psoriasis. Systematic psoriasis treatment is recommended for moderate to severe psoriasis. It is as well important to keep on using topical ointments while still under the systematic treatment.
Failing to conceive naturally doesn’t mean the end of your fertility. According to the HFEA, one in seven couples experience delays in conceiving. However, many people eventually fulfil their dream of becoming a parent through fertility treatment.
There are numerous reasons why people face difficulties when trying for a baby. Infertility is not just a woman’s problem as a third of cases are due to male fertility problems, e.g. low sperm count. There are also many other factors that can hinder conception including being over or underweight. Also, female fertility declines with age.
A blocked or damaged fallopian tube can also prevent a pregnancy occurring naturally as the egg cannot travel down the tube to meet the sperm. A popular form of fertility treatment to help combat this, and other problems, is In Vitro Fertilisation (IVF).
IVF treatment continues to rise with recent figures showing over 44,000 treatments taking place in 2006. The procedure involves fertilising the egg in a laboratory by putting the sperm and egg together in a small disposable dish. Once the embryos have formed, they are then placed inside the womb between two and five days later, in the hope of achieving a pregnancy.
The success rate of this technique increases year on year, with recent figures showing that the number of births increased by more than a thousand from the previous year to over 11,000.IVF is just one of many treatments carried out at fertility clinics. Other fertility treatments vary depending on the person’s needs.
Intrauterine Insemination (IUI)
IUI or artificial insemination is one of the least invasive treatments and is less expensive than IVF. This involves placing the sperm inside the woman’s uterus using a fine catheter. The procedure is undertaken after the egg is released, either in a natural or stimulated cycle.
Egg donation is a well-established form of fertility treatment using donated eggs, offering hope to many women who thought they would never fall pregnant. This procedure is recommended for women suffering from premature menopause; women treated for cancer, those suffering from a pelvic infection or endometriosis and women who were born without functioning ovaries such as those with Turner’s Syndrome.
Assisted hatching may be recommended for those who have already undergone fertility treatment, but have been unsuccessful. This form of treatment can be used for those with seemingly good quality embryos but who still have difficulty conceiving with IVF. The procedure was developed after it was observed that embryos which had a thicker outer shell (called the zona pellucid), had a lower chance of implanting during IVF. The process involves thinking or making a small hole in the zona pellicide making it easier for hatching to occur after IVF treatment.
Embryo Freezing and Frozen Embryo Transfer
Commonly, embryos that are produced during an IVF treatment but are surplus to requirements are frozen and stored for future use. The embryos are suspended in a solution designed to protect them and then placed in a tank of liquid nitrogen. Replacement of embryos via frozen embryo transfer may be undertaken through a natural or stimulated treatment cycle. Freezing embryos are also recommended to women undergoing cancer treatment..